Partial knee replacement (PKR) results in fast recovery and good knee mechanics and is ideal to treat medial knee osteoarthritis.\r\nCementless PKR depends on bone growing into the implant surface for long-term fixation. Implant loosening may occur due to\r\nhigh tensile strain resulted from large mechanical loads during rehab exercises. The purpose of this study is to investigate whether\r\nexternal fixations such as superior screw and frontal flange could reduce the tensile strain at the implant-bone interface. Three\r\nmedial PKRs were designed. The first PKR had no external fixations. A superior screw and a frontal flange were then added\r\nto the first PKR to form the second and third PKR designs, respectively. Finite element analysis was performed to examine the\r\ntensile strain at the implant-bone interface during weight-bearing exercises. The PKR with no external fixations exhibited high\r\ntensile strain at the anterior implant-bone interface. Both the screwed and flanged PKRs effectively reduced the tensile strain at the\r\nanterior implant-bone interface. Furthermore, the flanged PKR resulted in a more uniform reduction of the tensile strain than the\r\nscrewed PKR. In conclusion, external fixations are necessary to alleviate tensile strain at the implant-bone interface during knee\r\nrehab exercises
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